Description
What it is
TIRZ is a synthetic peptide that acts as an agonist at both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor. This dual activity sits between single-receptor agonists such as SEMA and triple agonists such as R3TA.
Research context
Used in metabolic and endocrine research to study combined incretin receptor activity and to compare signalling profiles across the agonist family.
Handling
Supplied lyophilised in a sealed 3 mL vial. Store sealed vials refrigerated and protected from light. Reconstitute with an appropriate sterile diluent immediately before use and keep reconstituted material cold. Avoid repeated freeze–thaw cycles.
Research use only. Not for human or veterinary use, and not for diagnostic or therapeutic application.

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